Document Type : Review
Authors
1
Botany and Microbiology Department, Faculty of Science, Beni-Suef University, Beni-Suef, 62511, Egypt
2
National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, Oxford, 38677, MS, United States
3
Biochemistry Division, Chemistry Department, Faculty of Science, Helwan University, Helwan, 11795, Egypt
4
Botany and Microbiology Department, Faculty of Science, Helwan University, Helwan, 11795, Egypt
5
National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, Oxford, 38677, MS, United States; Division of Pharmacognosy, Department of BioMolecular Sciences, School of Pharmacy, University of Mississippi, 38677, MS, United States
Abstract
Microalgae, as a diverse photosynthetic group of microorganisms with substantial ecological significance, have enormous potential for use in the food, medicine, and energy industries. However, current limitations in cost-effective production restrict their ubiquitous use. The purpose of this comprehensive mini-review is to investigate the impact of random mutagenesis techniques on microalgae and their biomolecule content, with the intention of improving the productivity and sustainability of cell factories for economically viable bioprocesses. Moreover, due to their simplicity and ease of cultivation in laboratory settings, microalgae serve as valuable model organisms for numerous scientific studies. This study investigates the effects of chemical and physical mutagens on microalgae in order to generate a heterogeneous microalgal population with advantageous traits such as increased lipids, proteins, and carotenoids, accelerated development, and enhanced nutrient absorption. This study findings will provide valuable insights into the manipulation of microalgae to increase biomolecule production and release their potential for a variety of applications.
Keywords
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